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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMF1 All Species: 7.58
Human Site: S169 Identified Species: 10.42
UniProt: P82094 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P82094 NP_009045.2 1093 122842 S169 E T L A A G T S S P K T E G K
Chimpanzee Pan troglodytes XP_526227 1093 122795 S169 E T L A A G T S S P K T E G K
Rhesus Macaque Macaca mulatta XP_001088711 1092 122828 S169 T L A A G T S S P K T E G K H
Dog Lupus familis XP_533766 1089 122761 L169 E T L A V D S L S P K T E G K
Cat Felis silvestris
Mouse Mus musculus B9EKI3 1091 121796 V169 A V G T P S P V P E D K H E E
Rat Rattus norvegicus NP_446123 1093 121882 P169 P A V G T P S P V P E G K R E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510334 1106 124384 K169 K S A V P L K K L E E A I P R
Chicken Gallus gallus O42184 1433 161009 K173 L P S G I P Q K T S P L A A K
Frog Xenopus laevis Q5PQ23 649 75475
Zebra Danio Brachydanio rerio NP_001003522 1136 126986 T169 L S E Q N S S T V E E Q M Q P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572360 933 103794 A121 G G D V P S V A K R L S E S S
Honey Bee Apis mellifera XP_394037 1326 150590 S196 E V N D C S N S N I N N P K I
Nematode Worm Caenorhab. elegans P02566 1966 225108 E751 D D K K K C A E A I M S K L V
Sea Urchin Strong. purpuratus XP_785821 1176 131318 D169 I L L Q D S D D S D E I D K E
Poplar Tree Populus trichocarpa XP_002303293 975 109171 D164 K V P E S V D D V Q G K E I S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q0WVL7 956 108335 K145 E T V V L D P K D D E P Q S Q
Baker's Yeast Sacchar. cerevisiae P47166 707 81153
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.5 93.1 N.A. 87.2 86.7 N.A. 81.2 21.7 22.6 59.7 N.A. 26.1 23.9 21 37.7
Protein Similarity: 100 99.4 99.1 96.1 N.A. 92.5 92 N.A. 88.3 39.9 37.3 74.6 N.A. 45.8 44.9 36.6 56.8
P-Site Identity: 100 100 13.3 73.3 N.A. 0 6.6 N.A. 0 6.6 0 0 N.A. 6.6 13.3 0 13.3
P-Site Similarity: 100 100 20 80 N.A. 6.6 40 N.A. 26.6 13.3 0 26.6 N.A. 20 20 26.6 33.3
Percent
Protein Identity: 25.8 N.A. N.A. 27.1 21.1 N.A.
Protein Similarity: 47.2 N.A. N.A. 45.4 39.4 N.A.
P-Site Identity: 6.6 N.A. N.A. 13.3 0 N.A.
P-Site Similarity: 20 N.A. N.A. 40 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 6 12 24 12 0 6 6 6 0 0 6 6 6 0 % A
% Cys: 0 0 0 0 6 6 0 0 0 0 0 0 0 0 0 % C
% Asp: 6 6 6 6 6 12 12 12 6 12 6 0 6 0 0 % D
% Glu: 30 0 6 6 0 0 0 6 0 18 30 6 30 6 18 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 6 6 6 12 6 12 0 0 0 0 6 6 6 18 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 6 0 6 % H
% Ile: 6 0 0 0 6 0 0 0 0 12 0 6 6 6 6 % I
% Lys: 12 0 6 6 6 0 6 18 6 6 18 12 12 18 24 % K
% Leu: 12 12 24 0 6 6 0 6 6 0 6 6 0 6 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 6 0 6 0 0 % M
% Asn: 0 0 6 0 6 0 6 0 6 0 6 6 0 0 0 % N
% Pro: 6 6 6 0 18 12 12 6 12 24 6 6 6 6 6 % P
% Gln: 0 0 0 12 0 0 6 0 0 6 0 6 6 6 6 % Q
% Arg: 0 0 0 0 0 0 0 0 0 6 0 0 0 6 6 % R
% Ser: 0 12 6 0 6 30 24 24 24 6 0 12 0 12 12 % S
% Thr: 6 24 0 6 6 6 12 6 6 0 6 18 0 0 0 % T
% Val: 0 18 12 18 6 6 6 6 18 0 0 0 0 0 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _